Spots Global Cancer Trial Database for A Phase 1, Study of BMF-500 in Adults With Acute Leukemia
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Trial Identification
Brief Title: A Phase 1, Study of BMF-500 in Adults With Acute Leukemia
Official Title: A Phase 1, Open-label, Dose-escalation, and Dose-expansion Study of BMF-500, an Oral Covalent FLT3 Inhibitor, in Adults With Acute Leukemia
Study ID: NCT05918692
Interventions
Study Description
Brief Summary: A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-500, an oral FLT3 inhibitor, in adult patients with acute leukemia.
Detailed Description: A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-500, an oral covalent FLT3 inhibitor, in adult patients with acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL) and Acute Mixed-Phenotype Leukemia (MPAL) who may or may not be on Antifungals.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Mayo Clinic, Phoenix, Arizona, United States
City of Hope National Medical Center, Duarte, California, United States
UCLA Department of Medicine, Los Angeles, California, United States
University of California, Davis, Sacramento, California, United States
University of California, San Francisco, San Francisco, California, United States
Colorado Blood Cancer Institute, Denver, Colorado, United States
Mayo Clinic, Jacksonville, Florida, United States
Winship Cancer Institute, Emory University, Atlanta, Georgia, United States
Northwestern Memorial Hospital, Chicago, Illinois, United States
University of Chicago Duchossois Center for Advanced Medicine (DCAM), Chicago, Illinois, United States
University of Kentucky - Markey Cancer Center, Lexington, Kentucky, United States
Mayo Clinic, Rochester, Minnesota, United States
John Theurer Cancer Center, Hackensack, New Jersey, United States
Montefiore Hospital - Moses Campus - BRANY - PPDs, Bronx, New York, United States
Roswell Park Comprehensive Cancer Center, Buffalo, New York, United States
Northwell Health Cancer Institute, New Hyde Park, New York, United States
East Carolina University, Greenville, North Carolina, United States
Cleveland Clinic Hospital, Cleveland, Ohio, United States
University of Oklahoma - Stephenson Cancer Center, Oklahoma City, Oklahoma, United States
Texas Oncology-PA USOR, Dallas, Texas, United States
MD Anderson Cancer Center, Houston, Texas, United States
Virginia Cancer Specialists, Gainesville, Virginia, United States
Fred Hutchinson Cancer Center, Seattle, Washington, United States
Contact Details
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