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Brief Title: Ribavirin and Hedgehog Inhibitor With or Without Decitabine in AML
Official Title: A Phase II, Multi-center, Open Label, Randomized Study of Ribavirin and Hedgehog Inhibitor With or Without Decitabine in Acute Myeloid Leukemia (AML)
Study ID: NCT02073838
Brief Summary: This is a research study of ribavirin which will be given in combination with vismodegib and/or decitabine. The purpose of this study is to see if patients respond to treatment when ribavirin is given with vismodegib alone or in combination with decitabine.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Jewish General Hospital, Montreal, Quebec, Canada
Name: Sarit Assouline, MD
Affiliation: Jewish General Hospital
Role: PRINCIPAL_INVESTIGATOR