Spots Global Cancer Trial Database for Non-Operative Management and Early Response Assessment in Rectal Cancer
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Trial Identification
Brief Title: Non-Operative Management and Early Response Assessment in Rectal Cancer
Official Title: Non-Operative Management and Early Response Assessment in Rectal Cancer
Study ID: NCT03904043
Conditions
Study Description
Brief Summary: The investigators' data from a phase I study of short course radiation therapy followed by chemotherapy showed 74% complete clinical response (cCR). Given the promising response rate, the investigators are evaluating short course radiation therapy (SCRT) followed by chemotherapy in a multi-institution phase II trial to validate the cCR rate of this treatment paradigm. SCRT has not been prospectively evaluated in non-operative management for patients with non-metastatic rectal adenocarcinoma.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Colorado, Aurora, Colorado, United States
Mayo Clinic, Rochester, Minnesota, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
University of Vermont Medical Center, Burlington, Vermont, United States
Contact Details
Name: Hyun Kim, M.D.
Affiliation: Washington University School of Medicine
Role: PRINCIPAL_INVESTIGATOR
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