Spots Global Cancer Trial Database for The Effects of the Water-exchanged Colonoscopy on Adenoma Detection Rate
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Trial Identification
Brief Title: The Effects of the Water-exchanged Colonoscopy on Adenoma Detection Rate
Official Title: The Effects of the Water-exchanged Colonoscopy on Adenoma Detection Rate: a Multicenter, Randomized, Single Blind, Control Trial
Study ID: NCT02135601
Interventions
Study Description
Brief Summary: Water exchange method has been shown to reduce medication requirement and pain experienced during colonoscopy. It may increase the adenoma detection rate (ADR). Water exchange provides salvage cleansing and the refractive index of water (n equals about 1.3) is larger than that of air, which creates optical distortion that likely contributes to objects appearing larger underwater, making smaller lesions easier to visualize and it may help draw attention to those smaller lesions during withdraw. These principles facilitate to the higher adenoma detection rate. There is a large number of literature on the adenoma detection rate during water exchange colonoscopy, but most studies have been conducted in only one centre, simple-size, and under sedation patients, the influence of adenoma detection rate under unsedation patients was unclear. The aim of this study is to compare the ADR of colonoscopy by using the water exchange method versus the conventional air method in unsedation patients in multiple centers in China.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Chaoyang Hospital, Beijing, Beijing, China
General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China
Union Hospital of Tongji Medical college, Wuhan, Hubei, China
Xijing Hospital of Digestive Diseases, Xi'an, Shaanxi, China
Renji Hospital, Shanghai, Shanghai, China
First Teaching Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China
Contact Details
Name: Yanglin Pan, M.D.
Affiliation: Air Force Military Medical University, China
Role: PRINCIPAL_INVESTIGATOR
Name: Felix W. Leung, M.D.
Affiliation: Sepulveda Ambulatory Care Center, VAGLAHS
Role: PRINCIPAL_INVESTIGATOR
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