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Spots Global Cancer Trial Database for The Effects of the Water-exchanged Colonoscopy on Adenoma Detection Rate

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: The Effects of the Water-exchanged Colonoscopy on Adenoma Detection Rate

Official Title: The Effects of the Water-exchanged Colonoscopy on Adenoma Detection Rate: a Multicenter, Randomized, Single Blind, Control Trial

Study ID: NCT02135601

Conditions

Adenoma
Pain

Interventions

Water colonoscopy

Study Description

Brief Summary: Water exchange method has been shown to reduce medication requirement and pain experienced during colonoscopy. It may increase the adenoma detection rate (ADR). Water exchange provides salvage cleansing and the refractive index of water (n equals about 1.3) is larger than that of air, which creates optical distortion that likely contributes to objects appearing larger underwater, making smaller lesions easier to visualize and it may help draw attention to those smaller lesions during withdraw. These principles facilitate to the higher adenoma detection rate. There is a large number of literature on the adenoma detection rate during water exchange colonoscopy, but most studies have been conducted in only one centre, simple-size, and under sedation patients, the influence of adenoma detection rate under unsedation patients was unclear. The aim of this study is to compare the ADR of colonoscopy by using the water exchange method versus the conventional air method in unsedation patients in multiple centers in China.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

Chaoyang Hospital, Beijing, Beijing, China

General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China

Union Hospital of Tongji Medical college, Wuhan, Hubei, China

Xijing Hospital of Digestive Diseases, Xi'an, Shaanxi, China

Renji Hospital, Shanghai, Shanghai, China

First Teaching Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China

Contact Details

Name: Yanglin Pan, M.D.

Affiliation: Air Force Military Medical University, China

Role: PRINCIPAL_INVESTIGATOR

Name: Felix W. Leung, M.D.

Affiliation: Sepulveda Ambulatory Care Center, VAGLAHS

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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