Spots Global Cancer Trial Database for Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia
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Trial Identification
Brief Title: Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia
Official Title: Genetic Polymorphisms in ALL Samples Submitted to Gene Array Analysis
Study ID: NCT01005277
Conditions
Interventions
Study Description
Brief Summary: This research study is looking at biomarkers in DNA samples from patients with acute lymphoblastic leukemia or acute myeloid leukemia. Studying samples of DNA from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
Detailed Description: PRIMARY OBJECTIVES: I. Collect DNA samples from patients with cytogenetically, well characterized, and uniformly treated acute lymphoblastic leukemia or acute myeloid leukemia for use in analysis of a wide range of host factors influencing etiology and outcome of the disease. II. Identify host factors that can be determined at onset of treatment to predict outcome of chemotherapy, and thus modify the therapy administered. OUTLINE: Previously collected DNA samples are analyzed for polymorphisms at a variety of loci. Gene expression and expression profiles are correlated with genotype and therapy outcomes.
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Childrens Oncology Group, Philadelphia, Pennsylvania, United States
Contact Details
Name: Stella Davies
Affiliation: Children's Oncology Group
Role: PRINCIPAL_INVESTIGATOR
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