Spots Global Cancer Trial Database for Paclitaxel in Treating Patients With Ovarian Stromal Cancer
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Trial Identification
Brief Title: Paclitaxel in Treating Patients With Ovarian Stromal Cancer
Official Title: Phase II Study of Paclitaxel for Ovarian Stromal Tumors as Second-Line Therapy
Study ID: NCT00006227
Interventions
Study Description
Brief Summary: This phase II trial studies the effectiveness of paclitaxel in treating patients who have ovarian stromal cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
Detailed Description: PRIMARY OBJECTIVES: I. To estimate the probability of clinical response and toxicity of paclitaxel as second-line chemotherapy in measurable disease patients with malignant tumors of the ovarian stroma. II. To evaluate the value of inhibin for predicting response. OUTLINE: Patients receive paclitaxel intravenously (IV) over 3 hours on day 1. Treatment continues every 21 days in the absence of disease progression or unacceptable toxicity. Patients are followed every 3 months for 2 years, then every 6 months for three years, and then annually thereafter.
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
Banner Thunderbird Medical Center, Glendale, Arizona, United States
Banner-University Medical Center Phoenix, Phoenix, Arizona, United States
Western Regional CCOP, Phoenix, Arizona, United States
Scottsdale Healthcare, Scottsdale, Arizona, United States
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Long Beach Memorial Medical Center-Todd Cancer Institute, Long Beach, California, United States
UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California, United States
Community Hospital of Los Gatos, Los Gatos, California, United States
Palo Alto Medical Foundation-Gynecologic Oncology, Mountain View, California, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, United States
UCSF Medical Center-Mount Zion, San Francisco, California, United States
North Colorado Medical Center, Greeley, Colorado, United States
McKee Medical Center, Loveland, Colorado, United States
Hartford Hospital, Hartford, Connecticut, United States
The Hospital of Central Connecticut, New Britain, Connecticut, United States
Beebe Medical Center, Lewes, Delaware, United States
Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States
Memorial University Medical Center, Savannah, Georgia, United States
Rush - Copley Medical Center, Aurora, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
Sudarshan K Sharma MD Limted-Gynecologic Oncology, Hinsdale, Illinois, United States
Joliet Oncology-Hematology Associates Limited, Joliet, Illinois, United States
Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States
Saint Vincent Hospital and Health Care Center, Indianapolis, Indiana, United States
Franciscan Saint Anthony Health-Michigan City, Michigan City, Indiana, United States
University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa, United States
University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States
Norton Hospital Pavilion and Medical Campus, Louisville, Kentucky, United States
Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States
Medical Center of Baton Rouge, Baton Rouge, Louisiana, United States
Union Hospital of Cecil County, Elkton, Maryland, United States
Borgess Medical Center, Kalamazoo, Michigan, United States
Bronson Methodist Hospital, Kalamazoo, Michigan, United States
West Michigan Cancer Center, Kalamazoo, Michigan, United States
University of Mississippi Medical Center, Jackson, Mississippi, United States
Keesler Medical Center, Keesler Air Force Base, Mississippi, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Women's Cancer Center of Nevada, Las Vegas, Nevada, United States
Cooper Hospital University Medical Center, Camden, New Jersey, United States
Jersey Shore Medical Center, Neptune, New Jersey, United States
Montefiore Medical Center-Einstein Campus, Bronx, New York, United States
Montefiore Medical Center - Moses Campus, Bronx, New York, United States
State University of New York Downstate Medical Center, Brooklyn, New York, United States
UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States
Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina, United States
Duke University Medical Center, Durham, North Carolina, United States
Brookview Research Incorporated, Winston-Salem, North Carolina, United States
Novant Health Forsyth Medical Center, Winston-Salem, North Carolina, United States
Novant Health Oncology Specialists, Winston-Salem, North Carolina, United States
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
Aultman Health Foundation, Canton, Ohio, United States
University of Cincinnati/Barrett Cancer Center, Cincinnati, Ohio, United States
Case Western Reserve University, Cleveland, Ohio, United States
MetroHealth Medical Center, Cleveland, Ohio, United States
Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States
Cleveland Clinic Foundation, Cleveland, Ohio, United States
Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
Riverside Methodist Hospital, Columbus, Ohio, United States
Mount Carmel Health Center West, Columbus, Ohio, United States
Kettering Medical Center, Kettering, Ohio, United States
Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States
Lake University Ireland Cancer Center, Mentor, Ohio, United States
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Oklahoma Cancer Specialists and Research Institute-Tulsa, Tulsa, Oklahoma, United States
Abington Memorial Hospital, Abington, Pennsylvania, United States
Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania, United States
Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, United States
Temple University Hospital, Philadelphia, Pennsylvania, United States
South Carolina Oncology Associates PA, Columbia, South Carolina, United States
Southeast Gynecologic Oncology Associates, Knoxville, Tennessee, United States
University of Tennessee Health Science Center, Memphis, Tennessee, United States
Brooke Army Medical Center, Fort Sam Houston, Texas, United States
Wilford Hall Medical Center, Lackland Air Force Base, Texas, United States
University of Virginia Cancer Center, Charlottesville, Virginia, United States
MultiCare Auburn Medical Center, Auburn, Washington, United States
Providence Regional Cancer System-Centralia, Centralia, Washington, United States
Saint Francis Hospital, Federal Way, Washington, United States
Saint Clare Hospital, Lakewood, Washington, United States
Providence - Saint Peter Hospital, Olympia, Washington, United States
Capital Medical Center, Olympia, Washington, United States
MultiCare Good Samaritan Hospital, Puyallup, Washington, United States
MultiCare Allenmore Hospital, Tacoma, Washington, United States
Northwest NCI Community Oncology Research Program, Tacoma, Washington, United States
West Virginia University Healthcare, Morgantown, West Virginia, United States
Tohoku University School of Medicine, Sendai, Aoba-ku, Japan
Sapporo Medical College, Sapporo, Chuo-ku, Japan
Hokkaido University Hospital, Sapporo, Hokkaido, Japan
Iwate Medical University School of Medicine, Morioka, Iwate, Japan
Kagoshima City Hospital, Kagoshima City, Kagoshima, Japan
Kawasaki Medical School, Okayama-Ken, Kurashiki, Japan
Keio University, Shinjuku-ku, Tokyo, Japan
National Hospital Organization-Kobe Medical Center, Kobe, , Japan
Shikoku Cancer Center, Matsuyama, , Japan
National Kyushu Cancer Center, Minami-ku, , Japan
Jikei University School of Medicine, Minato-ku, Tokyo, , Japan
Kindai University, Osaka, Osaka, , Japan
Tottori University, Tottori, , Japan
Contact Details
Name: Linda Van Le
Affiliation: NRG Oncology
Role: PRINCIPAL_INVESTIGATOR
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