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Brief Title: Safety, Tolerability & PK of KX2-361 in Subjects w Adv. Malignancies Refractory to Conventional Therapies
Official Title: A Phase 1 Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics of KX2-361 in Subjects With Advanced Malignancies That Are Refractory to Conventional Therapies
Study ID: NCT02326441
Brief Summary: The purpose of this study is to determine the safety and tolerability of the study drug KX2-361 and to determine how much of the study drug enters the bloodstream, in patients with advanced malignancies that have not responded to conventional therapies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Roswell Park Cancer Institute, Buffalo, New York, United States
Cleveland Clinic, Taussig Cancer Institute, Cleveland, Ohio, United States
UTHSCSA Cancer Therapy and Research Center, San Antonio, Texas, United States
Name: David Cutler, MD
Affiliation: Kinex Pharmaceutical
Role: STUDY_DIRECTOR