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Brief Title: Cabozantinib in Patients With Advanced Hepatocellular Carcinoma With Child Pugh Class B Cirrhosis After First-Line Therapy
Official Title: Phase 1/2 Trial to Evaluate Cabozantinib in Patients With Advanced Hepatocellular Carcinoma With Child Pugh Class B Cirrhosis After First-Line Therapy
Study ID: NCT04497038
Brief Summary: The aim of this study is to determine the safety and efficacy of cabozantinib in the management of unresectable or metastatic hepatocellular carcinoma (HCC) with underlying Child-Pugh class B cirrhosis.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Northwestern University, Chicago, Illinois, United States
University of Chicago, Chicago, Illinois, United States
University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, United States
University of Texas Southwestern Medical Center, Dallas, Texas, United States
Name: Vaibhav Sahai, MBBS, MS
Affiliation: University of Michigan
Role: PRINCIPAL_INVESTIGATOR