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Brief Title: Open Label, Dose Escalation Trial of Oral Eg5 Kinesin-spindle Inhibitor 4SC-205 in Patients With Advanced Malignancies
Official Title: Open Label, Dose Escalation Trial of Oral 4SC-205 in Patients With Advanced Malignancies: First-In-Man Study of a Newly Developed, Oral Inhibitor of Kinesin-spindle Protein, Eg5
Study ID: NCT01065025
Brief Summary: The purpose of the study is to investigate safety and tolerability of repeated ascending oral doses of 4SC-205 in patients with advanced and incurable solid tumors or malignant lymphomas.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Universitätsklinikum Essen, Essen, , Germany
Klinik für Tumorbiologie an der Albert-Ludwigs-Universität Freiburg (KTB), Freiburg, , Germany
Name: Klaus Mross, PD Dr. med.
Affiliation: Klinik für Tumorbiologie an der Albert-Ludwigs-Universität Freiburg (KTB)
Role: PRINCIPAL_INVESTIGATOR