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Brief Title: PK and Drug Interaction Study of Utidelone Plus Capecitabine in Patients With Advanced Breast Cancer
Official Title: Open, Multicenter, Phase Ic Clinical Study on the Pharmacokinetics and Drug Interactions of Utidelone Plus Capecitabine in Patients With Recurrent and Metastatic Breast Cancer
Study ID: NCT05052437
Brief Summary: This trial is an open, multi-center, phase Ic clinical study on the pharmacokinetics and drug interactions of utidelone injection combined with capecitabine in patients with recurrent and metastatic breast cancer. The purpose of this trial is: 1. To evaluate the pharmacokinetic characteristics of continuous intravenous administration of utidelone. 2. To evaluate the drug interaction of utidelone and capecitabine.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Hunan Cancer Hospital, Changsha, Hunan, China
The Third Xiangya Hospital of Central South University, Changsha, Hunan, China
Name: Quchang Ouyang, MD
Affiliation: Hunan Cancer Hospital
Role: PRINCIPAL_INVESTIGATOR