Spots Global Cancer Trial Database for Futibatinib and Pembrolizumab Combination in the Treatment of Advanced or Metastatic Urothelial Carcinoma
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Trial Identification
Brief Title: Futibatinib and Pembrolizumab Combination in the Treatment of Advanced or Metastatic Urothelial Carcinoma
Official Title: A Phase 2 Study Evaluating Futibatinib (TAS 120) Plus Pembrolizumab in the Treatment of Advanced or Metastatic Urothelial Carcinoma
Study ID: NCT04601857
Interventions
Study Description
Brief Summary: The purpose of the trial is to evaluate the antitumor activity and confirm the safety for the combination of Fibroblast Growth Factor Receptor (FGFR) inhibitor futibatinib and anti-programmed cell death-1 (PD-1) antibody pembrolizumab in patients with advanced or metastatic urothelial cancer who are not candidates to receive a platinum-based treatment regimens.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
Henry Ford Hospital, Detroit, Michigan, United States
Comprehensive Care Centers of Nevada, Las Vegas, Nevada, United States
ICANS - Institut de cancérologie de Strasbourg Europe, Strasbourg, Bas-Rhin, France
Institut Paoli Calmettes - Hôpital de jour, Marseille, Bouches-du-Rhône, France
Centre Georges-François Leclerc, Dijon, Côte d'Or, France
Centre Leon Berard - departement d'oncologie medicale, Lyon, Rhone, France
Centre Regional de Lutte Contre le Cancer de Lorraine, Vandœuvre-lès-Nancy, , France
Institut De Cancerologie Gustave Roussy, Villejuif, , France
ALTHAIA, Xarxa Assistencial Universitària de Manresa, Manresa, Brcelona, Spain
Hospital Clinic de Barcelona, Barcelona, , Spain
Hospital de La Santa Creu i Sant Pau, Barcelona, , Spain
Hospital Universitario Vall d'Hebrón, Barcelona, , Spain
Hospital Universitario Reina Sofia, Córdoba, , Spain
Hospital Universitario HMN Sanchinarro, Madrid, , Spain
Hospital Universitario Marqués de Valdecilla, Santander, , Spain
Hospital la Fe, Valencia, , Spain
Contact Details
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