Spots Global Cancer Trial Database for The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Trial
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Trial Identification
Brief Title: The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Trial
Official Title: A Multiple Parallel Cohort, Multi-centre Phase IIa Trial Aiming to Provide Proof of Principle Efficacy for Designated Targeted Therapies in Patients With Advanced Breast Cancer Where the Targetable Mutation is Identified Through ctDNA
Study ID: NCT03182634
Conditions
Study Description
Brief Summary: plasmaMATCH is a multi-centre phase IIa umbrella trial platform consisting of a ctDNA screening component and a therapeutic component. plasmaMATCH aims to assess whether ctDNA screening can be used to detect patient subgroups who will be sensitive to targeted therapies, and will also assess the safety and activity of the targeted treatments.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Royal Marsden Hosital, Sutton, England, United Kingdom
Royal Bournemouth Hospital, Bournemouth, , United Kingdom
Bristol Haematology and Oncology Centre, Bristol, , United Kingdom
Addenbrooke's Hospital, Cambridge, , United Kingdom
Velindre Cancer Centre, Cardiff, , United Kingdom
Western General Hospital, Edinburgh, , United Kingdom
Royal Devon and Exeter Hospital, Exeter, , United Kingdom
Beatson West of Scotland Cancer Centre, Glasgow, , United Kingdom
Clatterbridge Cancer Centre, Liverpool, , United Kingdom
Barts Health Trust, London, , United Kingdom
Royal Marsden Hospital, London, , United Kingdom
University College Hospital London, London, , United Kingdom
Kent Oncology Centre, Maidstone, , United Kingdom
Christie Hospital, Manchester, , United Kingdom
Churchill Hospital, Oxford, , United Kingdom
Derriford Hospital, Plymouth, , United Kingdom
Weston Park Hospital, Sheffield, , United Kingdom
University Hospitals Southampton NHS Foundation Trust, Southampton, , United Kingdom
Royal Cornwall Hospital, Truro, , United Kingdom
Contact Details
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