Spots Global Cancer Trial Database for Safety Study of SGX523, a Small Molecule Met Inhibitor, to Treat Solid Tumors
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Trial Identification
Brief Title: Safety Study of SGX523, a Small Molecule Met Inhibitor, to Treat Solid Tumors
Official Title: A Phase I, Multi-Center, Open Label, Dose Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Orally Administered SGX523, a Small Molecule Anti-Cancer Agent, Ona Twice Daily, Interrupted Schedule in Patients With Advanced Cancer
Study ID: NCT00607399
Conditions
Interventions
Study Description
Brief Summary: SGX523 is a drug which acts by blocking the function of an enzyme called MET. MET activity may be important in growth and survival of some types of cancer. This Phase I trial is studying the safety, side effects, and best dose of SGX523 when given to patients with advanced cancer, and how well it inhibits MET activity in tumors.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Scottsdale Healthcare, Scottsdale, Arizona, United States
Premiere Oncology, Arizona, Scottsdale, Arizona, United States
Contact Details
Name: Michael Gordon, MD
Affiliation: Premier Onocology, Arizona
Role: PRINCIPAL_INVESTIGATOR
Name: Ramesh Ramanathan, MD
Affiliation: Scottsdale Healthcare
Role: PRINCIPAL_INVESTIGATOR
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