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Brief Title: A Study Investigating AGEN1777 in Participants With Advanced Solid Tumors
Official Title: A Phase 1 Study Investigating AGEN1777 as a Single-Agent and in Combination With a PD-1 Inhibitor in Patients With Advanced Solid Tumors
Study ID: NCT05025085
Brief Summary: This study is a multicenter, Phase 1 study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics of AGEN1777 as a single agent and when used in combination with a PD-1 inhibitor in participants with advanced, metastatic solid tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Local Institution - 165, Grand Rapids, Michigan, United States
START Midwest, Grand Rapids, Michigan, United States
Local Institution - 024, Southfield, Michigan, United States
Local Institution - 072, Cincinnati, Ohio, United States
University of Cincinnati Cancer Center, Cincinnati, Ohio, United States
Providence Cancer Institute, Portland, Oregon, United States
Lifespan Cancer Institute, Providence, Rhode Island, United States
Local Institution - 0001, Providence, Rhode Island, United States
Local Institution - 164, Dallas, Texas, United States
Mary Crowley Cancer Research, Dallas, Texas, United States
MD Anderson Cancer Center Thoracic-Head & Neck Med Onc, Houston, Texas, United States
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR