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Spots Global Cancer Trial Database for Intrathecal Morphine Administration Using Implantable Pump With Continuous or Programmable Flow

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Trial Identification

Brief Title: Intrathecal Morphine Administration Using Implantable Pump With Continuous or Programmable Flow

Official Title: Comparison of Two Types of Intrathecal Morphine Administration by Pump for Analgesia in Cancer Patients With Failure of Conventional Analgesic Therapy.

Study ID: NCT01567345

Study Description

Brief Summary: The aim of this study is to compare intrathecal morphine administration: using a pump with continuous or programmable flow.

Detailed Description: Cancer is frequently associated with pain. In spite of recent improvements in cancer related pain treatment, incidence of cancerous chronic pain did not decrease. Indeed, 15 to 20% of patients are still suffering from intractable pain despite an optimal symptom management. Treatment of cancer pain is generally based on the WHO analgesic ladder according to 3 steps. Patients with advanced cancer are often treated at WHO step 3 analgesics, i.e. morphine and its derivatives, at high dosages. But increasing the dosage of opioids also leads to accentuation of their adverse events and the corresponding risks. At this stage of the disease, in patients with failure of conventional analgesic therapy, intrathecal injection of analgesics can be decided in order to relieve pain. 2 types of pumps allow intrathecal morphine administration : continuous or programmable flow. In this study, we want to compare the quality of analgesia obtained through these 2 flows.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

ICO Paul Papin, Angers, , France

Institut Bergonié, Bordeaux, , France

Centre Hospitalier, Laon, , France

Centre Oscar Lambret, Lille, , France

Hôpital Laennec, Nantes, , France

Polyclinique, Poitiers, , France

Contact Details

Name: Denis Dupoiron, MD

Affiliation: Institut Cancerologie de l'Ouest

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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