Spots Global Cancer Trial Database for A First in Man Study of MABp1 in Patients With Advanced Cancers
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Trial Identification
Brief Title: A First in Man Study of MABp1 in Patients With Advanced Cancers
Official Title: A Phase 1 Study of MABp1 in Patients With Advanced Cancers
Study ID: NCT01021072
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to block interleukin-1 alpha activity with a True Human monoclonal antibody, thus interrupting the inflammatory response that supports tumor growth/metastasis and which drives the cachexic process. An adaptive design will be employed which will allow for the exploration of different dosing regimens, as well as tumor types that show preliminary evidence of efficacy.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
M.D. Anderson Cancer Institute, Houston, Texas, United States
MD Anderson Cancer Center, Houston, Texas, United States
Contact Details
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