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Brief Title: mFOLFIRI as the Second Line Chemotherapy for Advanced Esophageal Carcinoma After Failure of 1st Line Treatment of Paclitaxel/DDP : a Phase II Single Center Prospective Clinical Trial
Official Title:
Study ID: NCT01044420
Brief Summary: There are few studies about 2nd line treatment in advanced esophageal carcinoma(AEC), some showed that irinotecan may be effective. The investigators previous study has shown the efficacy and safety of paclitaxel/cisplatin as 1st line treatment, so in this phase II study, the investigators would like to observe the efficacy and safety of Irinotecan/5FU/leucovorin as 2nd line treatment if AEC after failure to 1st treatment of PTX/DDP.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Zhang Xiaodong, Beijing, Beijing, China
Name: shen lin, MD
Affiliation: peking university, school of oncology, department of GI oncology
Role: STUDY_CHAIR
Name: zhang xiaodong, MD
Affiliation: Peking University, school of oncology, department of GI oncology
Role: PRINCIPAL_INVESTIGATOR