The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Brief Title: A Study of Anlotinib Hydrochloride Capsule Combined With AK105 Injection in Subject With Advanced Gastric and Gastro-oesophageal Junction Adenocarcinoma
Official Title: A Randomized, Open-label, Controlled, Multicenter Phase III Study of Hydrochloride Capsule Combined With AK105 Injection Versus Standard Second-line Chemotherapy for Advanced Gastric and Gastro-oesophageal Junction Adenocarcinoma
Study ID: NCT04385550
Brief Summary: This is a randomized, controlled, open-label, multicenter study to evaluate efficacy of AK105 injection combined with Anlotinib Hydrochloride Capsules versus standard second-line chemotherapy. Patients are treated with AK105 injection combined with Anlotinib Hydrochloride Capsules or standard second-line chemotherapy, with 1:1 random ratio.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing, Beijing, China
The Sixth Medical Center of PLA General Hospital, Beijing, Beijing, China
Peking University Shougang Hospital, Beijing, Beijing, China
Beijing Luhe Hospital Capital Medical University, Beijing, Beijing, China
Beijing Tsinghua Changgung Hospital, Beijing, Beijing, China
Fujian Provincial Cancer Hospital, Fuzhou, Fujian, China
Quanzhou First Hospital, Quanzhou, Fujian, China
The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China
Zhongshan Hospital Xiamen University, Xiamen, Fujian, China
The First Hospital of Lanzhou University, Lanzhou, Gansu, China
Gansu Wuwei Tumour Hospital, Wuwei, Gansu, China
Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China
The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China
Guangxi Medical University Affiliated Tumor Hospital, Nanning, Guangxi Zhuang Autonomous Region, China
The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
AnYang Tumor Hospital, Anyang, Henan, China
Xinxiang Central Hospital, Xinxiang, Henan, China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
Henan Cancer Hospital, Zhengzhou, Henan, China
Union Hospital,Tongji Medical College,Huazhong University of Science and Technology, Wuhan, Hubei, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China
Hubei Cancer Hospital, Wuhan, Hubei, China
Xiangya Hospital Central South University, Changsha, Hunan, China
The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
Hunan Cancer Hospital, Changsha, Hunan, China
Jiangsu Cancer Hospital, Nanjing, Jiangsu, China
Jiangsu Province Hospital, Nanjing, Jiangsu, China
Nantong Cancer Hospital, Nantong, Jiangsu, China
Wuxi People's Hospital, Wuxi, Jiangsu, China
Hospital of Jiangnan University, Wuxi, Jiangsu, China
The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
Liaoning Cancar Hospital, Shenyang, Liaoning, China
People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, Ningxia Hui Autonomous Region, China
Shandong Cancer Hospital, Jinan, Shandong, China
Shanghai General Hospital, Shanghai, Shanghai, China
Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi, China
The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China
First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China
Tianjin Medical University General Hospital, Tianjing, Tianjing, China
Tianjin Medical University Cancer Institute and Hospital, Tianjing, Tianjing, China
The First People's Hospital of kashi region, Kashi, XinJiang Uighur Autonomous Region, China