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Brief Title: Phase I Study of Daily RAD001 in Combination With Mitomycin C in Patients With Advanced Gastric Cancer or Cancer of the Esophagogastric Junction
Official Title: Phase I Study of Daily RAD001 Administered Orally in Combination With Mitomycin C, Administered Every Three Weeks to Patients With Advanced Gastric Cancer or Cancer of the Esophagogastric Junction
Study ID: NCT01042782
Brief Summary: Patients with advanced gastric cancer are treated with a combination of RAD001 (everolimus) and Mitomycin C.
Detailed Description: The purpose of this monocenter, single-arm, phase I trial is to determine the maximum-tolerated-dose, dose-limiting toxicity (DLT) and preliminary efficacy and safety of RAD001 in combination with Mitomycin C in patients with advanced gastric cancer.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Krankenhaus Nordwest, Frankfurt, , Germany
Name: Salah-Eddin Al-Batran, MD
Affiliation: Krankenhaus Nordwest
Role: PRINCIPAL_INVESTIGATOR