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Brief Title: Efficacy and Safety Study of Sorafenib Plus Pravastatin to Treat Advanced Hepatocarcinoma
Official Title: Phase-II, Multicenter, Randomized, Double-Blind, Parallel-Group Trial to Compare the Efficacy and Safety of Sorafenib Plus Pravastatin Against Sorafenib Plus Placebo in Patients With Advanced Hepatocarcinoma
Study ID: NCT01418729
Brief Summary: The purpose of this study is to evaluate the overall survival (OS) in order to assess the efficacy and safety of pravastatin as adjuvant treatment to sorafenib.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Hospital Donostia, Instituto Biodonostia, San Sebastian, Gipuzkoa, Spain
Name: Juan I Arenas, MD,PHD
Affiliation: Hospital Donostia
Role: STUDY_CHAIR
Name: Javier Bustamante Scheneider, MD
Affiliation: Hospital de Cruces
Role: PRINCIPAL_INVESTIGATOR
Name: Trinidad Serrano Aullo, MD, PHD
Affiliation: Hospital Clínico Universitario Lozano Blesa
Role: PRINCIPAL_INVESTIGATOR
Name: Mercedes Iñarrairaegui Bastarrica, MD
Affiliation: Clínica Universitaria de Navarra
Role: PRINCIPAL_INVESTIGATOR
Name: Sonia Blanco Sampascual, MD
Affiliation: Hospital de Basurto
Role: PRINCIPAL_INVESTIGATOR
Name: Maria Varela, MD, PHD
Affiliation: Hospital Central de Asturias
Role: PRINCIPAL_INVESTIGATOR
Name: Oscar Nuñez, MD
Affiliation: Hospital Infanta Sofia
Role: PRINCIPAL_INVESTIGATOR