Spots Global Cancer Trial Database for A Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepatocellular Carcinoma (HCC)
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Trial Identification
Brief Title: A Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepatocellular Carcinoma (HCC)
Official Title: A Randomized, Controlled, Open-label, Multicenter Phase III Clinical Trial of AK105 Injection Combined With Anlotinib Hydrochloride Capsules Versus Sorafenib in Subjects With Advanced Hepatocellular Carcinoma (HCC)
Study ID: NCT04344158
Conditions
Study Description
Brief Summary: This is a randomized, controlled, open-label, multicenter study to evaluate efficacy of AK105 injection combined with Anlotinib Hydrochloride Capsules versus Sorafenib. Patients are treated with AK105 injection combined with Anlotinib Hydrochloride Capsules or Sorafenib, with 2:1 random ratio. Every 21 days is a treatment cycle.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China
Anhui Provincial Hospital, Hefei, Anhui, China
Anhui Provincial Cancer Hospital, Hefei, Anhui, China
Beijing Ditan Hospital.Capital Medical University, Beijing, Beijing, China
Beijing YouAn Hospital.Capital Medical University, Beijing, Beijing, China
Beijing Cancer Hospital, Beijing, Beijing, China
Peking Union Medical College Hospital, Beijing, Beijing, China
Chinese Pla General Hospital, Beijing, Beijing, China
Beijing Tsinghua Changgung Hospital, Beijing, Beijing, China
Beijing Luhe Hospital.Capital Medical University, Beijing, Beijing, China
The Second Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China
The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Fujian Provincial Cancer Hospital, Fuzhou, Fujian, China
The first hospital of Lanzhou University, Lanzhou, Gansu, China
Gansu Wuwei Tumour Hospital, Wuwei, Gansu, China
Sun Yat-sen University Cancar Center, Guangzhou, Guangdong, China
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China
The First Affiliated Hospital，Sun Yat-sen University, Guangzhou, Guangdong, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China
The First Affiliated Hospital，Sun Yat-sen University, Guangzhou, Guangdong, China
Guangxi Medical University Affiliated Tumor Hospital, Nanning, Guangxi Zhuang Autonomous Region, China
The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, China
Hainan General Hospital, Haikou, Hainan, China
Cangzhou Central Hospital, Cangzhou, Hebei, China
The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China
Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang, China
Henan Province People's Hospital, Zhengzhou, Henan, China
Henan Cancer Hospital, Zhengzhou, Henan, China
Xiangya Hospital Central South University, Changsha, Hunan, China
Hunan Cancar Hospital, Changsha, Hunan, China
Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China
Zhongshan Hospital, Fuadn University, Shanghai, Shanghai, China
The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China
Tangdu Hospital of the Fourth Military Medical University of the People's Liberation Army of China, Xi'an, Shanxi, China
First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China
Shanxi Provincial Cancer Hospital, Xi'an, Shanxi, China
West China School of Medical Sichuan University, Chengdu, Sichuan, China
Affiliated Hospital of Chengdu University, Chengdu, Sichuan, China
Tianjin Medical University Cancar institute & Hospital, Tianjin, Tianjin, China
Tianjin Third Central Hospital, Tianjin, Tianjin, China
Tianjin First Central Hospital, Tianjin, Tianjin, China
Tianjin Second People's Hospital, Tianjin, Tianjin, China
The First Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang Uygur Autonomous Region, China
Contact Details
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