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Brief Title: A Study Investigating the Efficacy and Safety of Ociperlimab and Tislelizumab and BAT1706 Combinations in Patients With Advanced HCC
Official Title: A Phase 2, Randomized, Open-labeled Clinical Study Investigating the Efficacy and Safety of Ociperlimab in Combination With Tislelizumab Plus BAT1706 and of Tislelizumab Plus BAT1706 as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma
Study ID: NCT04948697
Brief Summary: This is a Phase 2, randomized, multicenter, open-label, 2-arm study to investigate the efficacy and safety of ociperlimab in combination with tislelizumab plus BAT1706, and tislelizumab plus BAT1706, as first-line treatment in participants with advanced HCC.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, Beijing, China
Beijing Cancer Hospital, Beijing, Beijing, China
Chongqing University Three Gorges Hospital, Chongqing, Chongqing, China
Fujian Cancer Hospital, Fuzhou, Fujian, China
Mengchao Hepatobiliary Hospital of Fujian Medical University, Gulou, Fuzhou, China
Guangdong Provincial People's Hospital, Guangzhou, Guangdong, China
The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
Hubei Cancer Hospital, Wuhan, Hubei, China
Hunan Cancer Hospital, Changsha, Hunan, China
The First Hospital of China Medical University, Shenyang, Liaoning, China
Shengjing Hospital of China Medical University, Shenyang, Liaoning, China
Fudan University Zhongshan Hospital, Shanghai, Shanghai, China
West China Hospital Sichuan University, Chengdu, Sichuan, China
Tianjin Medical University Cancer institute & Hospital, Tianjin, Tianjin, China
Tianjin Third Central Hospital, Tianjin, Tianjin, China
The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Nanfang Hospital of Southern Medical University, Guangdong, , China
The Second Affiliated Hospital of Nanchang University, Jiangxi, , China
Hwa Mei Hospital, University of Chinese Academy of Sciences, Zhejiang, , China
National Cheng Kung University Hospital, Tainan, , Taiwan
Chi Mei Medical Center, Tainan, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Chang Gung Medical Foundation (CGMF) - Linkou Branch, Taoyuan, , Taiwan
Name: Vincent Li, MD
Affiliation: BeiGene, Ltd.
Role: STUDY_DIRECTOR