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Brief Title: A Study of TAE+HAIC Combined With Camrelizumab and Apatinib in the Treatment of Advanced Hepatocellular Carcinoma
Official Title: Single-arm, Prospective Clinical Study of TAE+HAIC Combined With Camrelizumab and Apatinib in the Treatment of Advanced Hepatocellular Carcinoma With High Tumor Load
Study ID: NCT06363825
Brief Summary: To evaluate the efficacy and safety of TAE+HAIC combined with camrelizumab and apatinib in the treatment of advanced liver cancer with high tumor load
Detailed Description: At present, there are no prospective clinical studies using the combination regimen (TAE+HAIC+ Apatinib + camrelizumab) in the treatment of advanced liver cancer. Therefore, in this study, investigators designed a single-arm, prospective, multicenter, phase Ⅱ clinical study of arterial infusion of TAE+HAIC+ Apatinib + camrelizumab in the treatment of advanced liver cancer with high tumor load, to explore the safety and efficacy of this regimen. If study gets positive results, it will provide a reference for the subsequent phase Ⅲ clinical trial design, which is expected to provide a new effective approach for the treatment of advanced liver cancer.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Xinhua Chen, Fuzhou, , China
Name: Zhong Tang
Affiliation: Nanping First Hospital of Fujian Province
Role: PRINCIPAL_INVESTIGATOR
Name: Yingchun Li
Affiliation: Longyan First Hospital, Affiliated to Fujian Medical University
Role: PRINCIPAL_INVESTIGATOR
Name: Peishu Huang
Affiliation: Shanghai Sixth Hospital Fujian Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Lei Yu
Affiliation: Sanming First Hospital
Role: PRINCIPAL_INVESTIGATOR