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Spots Global Cancer Trial Database for Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Lung Cancer

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Trial Identification

Brief Title: Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Lung Cancer

Official Title: Phase II Randomized Comparison Clinical Trial of Target Activated CIK for Advanced Lung Cancer

Study ID: NCT03501056

Study Description

Brief Summary: This is a phase II Randomized comparison clinical trial of activated CIK armed with anti-CD3-MUC1 bispecific antibody for advanced lung cancer. And the aim of this research is to study the clinical efficacy and safety of activated CIK armed with anti-CD3-MUC1 bispecific antibody for lung cancer.

Detailed Description: Primary pulmonary carcinoma is one of the most common malignancies in China, ranking first in all malignant tumors and mortality.Immunetherapy is considered to be one of the most promising means of human against cancer. This is a phase II clinical trial of single- center, The investigators plan to recruit for 90 patients with advanced lung cancer,and all patients are divided into three groups.one group will receive cryotherapy, one group will receive conventional therapy,and the rest one will receive mixed liquor of activated CIK and anti-CD3-MUC1 bispecific antibody together with cryotherapy. The result of this study was statistic and analysed with the record of Response Evaluation Criteria In Solid Tumors(RECIST1.1) evaluation standard.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Institutional Review Board of Guangzhou Fuda Cancer Hospital, Guangzhou, Guangdong, China

Contact Details

Name: Jibing Chen, Doctor

Affiliation: Guangzhou Fuda Cancer Hospital

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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