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Brief Title: Maintenance Study on the Long Term Safety of XL999
Official Title: A Maintenance Study Evaluating the Long Term Safety of XL999 Administered Intravenously to Subjects With Advanced Malignancies Previously Enrolled in Other XL999 Studies
Study ID: NCT00955084
Brief Summary: The primary objective of this study is to allow rollover of the two remaining subjects from the other XL999 studies to continue to receive XL999. The secondary objectives of this study are as follows: * To evaluate tumor response after long term repeat administration of XL999 in two subjects rolled over from other XL999 studies. * To characterize the long term safety and tolerability of XL999 after repeat administration in two subjects rolled over from other XL999 studies. * To characterize the long term effects of XL999 on cardiac function after repeat administration in two subjects rolled over from other XL999 studies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Hematology Oncology Associates of Rockland Union State Bank Cancer Center, Nyack, New York, United States
University of Texas Cancer Center, San Antonio, Texas, United States
Name: Charles W. Finn, PhD
Affiliation: Symphony Evolution, Inc.
Role: STUDY_DIRECTOR