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Spots Global Cancer Trial Database for A Phase 1b Study Evaluating AMG 232 Alone and in Combination With Trametinib in Acute Myeloid Leukemia

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Trial Identification

Brief Title: A Phase 1b Study Evaluating AMG 232 Alone and in Combination With Trametinib in Acute Myeloid Leukemia

Official Title: A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 232 Alone and in Combination With Trametinib in Adult Subjects With Relapsed/Refractory Acute Myeloid Leukemia

Study ID: NCT02016729

Interventions

AMG 232
Trametinib

Study Description

Brief Summary: Open-label, sequential dose escalation and expansion study of AMG 232 in subjects with acute myeloid leukemia.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Research Site, Birmingham, Alabama, United States

Research Site, Buffalo, New York, United States

Research Site, Charlotte, North Carolina, United States

Research Site, Salt Lake City, Utah, United States

Research Site, Seattle, Washington, United States

Contact Details

Name: MD

Affiliation: Amgen

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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