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Spots Global Cancer Trial Database for Clinical Study of HMPL-653 in Treatment of Advanced Malignant Solid Tumors and TGCT

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Trial Identification

Brief Title: Clinical Study of HMPL-653 in Treatment of Advanced Malignant Solid Tumors and TGCT

Official Title: A Multicenter, Open-label, Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMPL-653 in Treatment of Patients With Advanced Malignant Solid Tumors and Tenosynovial Giant Cell Tumor

Study ID: NCT05277454

Interventions

HMPL-653

Study Description

Brief Summary: To evaluate the safety and tolerability of HMPL-653 in patients with advanced solid tumors who have failure of standard of care or can not tolerate standard of care or those with TGCT, and to determine the maximum tolerated dose (MTD) and/or the recommended phase II clinical study dose (RP2D) of HMPL-653 in patients with advanced solid tumors.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Jilin Provincial Cancer Hospital, Chang chun, , China

Harbin Medical University Cancer Hospital, Harbin, , China

Linyi Cancer Hospital, Linyi, , China

Henan Cancer Hospital, Zhengzhou, , China

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, , China

Contact Details

Name: Ying Cheng, Prof

Affiliation: Jilin Provincial Cancer Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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