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Brief Title: Phase I Clinical Trial of TQB3915 Tablets in Subjects With Advanced Malignant Solid Tumors
Official Title: Phase I Clinical Trial of TQB3915 Tablets in Subjects With Advanced Malignant Solid Tumors
Study ID: NCT05416359
Brief Summary: TQB3915 is a selective estrogen receptor covalent antagonist, by covalently binding to estrogen receptor, by changing the conformation of ERα, blocking intracellular signal transmission, thereby inhibiting the growth of tumor cells.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Sun Yat-Sen University Cancer Canter, Guangzhou, Guangdong, China
Henan Cancer Hospital, Zhengzhou, Henan, China
First Affiliated Hospital with Nanjin Medical University (Jiangsu Province Hospital), Nanjing, Jiangsu, China