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Brief Title: A Study of AK130 in Patients With Advanced Malignant Tumors
Official Title: A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Anti-tumor Activity of AK130 (TIGIT/TGF-β Bifunctional Fusion Protein) in Patients With Advanced Malignant Tumors
Study ID: NCT05653284
Brief Summary: A Phase I open label, dose-escalation and expansion study to evaluate the safety, tolerability, pharmacokinetics and anti-tumor activity of AK130 (TIGIT/TGF-β bifunctional fusion protein) in patients with advanced malignant tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Name: Jinming Yu
Affiliation: The Cancer Hospital Affiliated to Shandong First Medical University
Role: PRINCIPAL_INVESTIGATOR