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Brief Title: A Study of Lorlatinib in Subjects With ROS1-Positive Non-Small Cell Lung Cancer
Official Title: A Phase 2, Multi-Center, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lorlatinib Monotherapy in Crizotinib and Platinum-based Chemotherapy Treated Locally Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer Subjects in China
Study ID: NCT05297890
Brief Summary: A Phase 2, Multi-Center, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Lorlatinib Monotherapy in Crizotinib and Platinum-based Chemotherapy Treated Locally Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer (NSCLC)Subjects in China
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Guangdong Provincial People's hospital, Guangzhou, Guangdong, China
Beijing Cancer Hospital, Beijing, , China
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, , China
The First Hospital of Jilin University, Changchun, , China
Hunan Cancer Hospital, Changsha, , China
Sichuan Cancer Hospital & Institute, Chengdu, , China
West China Hospital of Sichuan University, Chengdu, , China
Chinese PLA Army Medical Center, Chongqing, , China
Fujian Cancer Hospital, Fuzhou, , China
Sun Yat-sen University Cancer Center, Guangzhou, , China
The first Affiliated hospital, Sun Yat-Sen University, Guangzhou, , China
Zhejiang Cancer Hospital, Hangzhou, , China
Harbin Medical University Cancer Hospital, Harbin, , China
The First Affiliated Hospital of Anhui Medical University, Hefei, , China
Shandong Cancer Hospital&Institute, Jinan, , China
Yunnan Cancer Hospital, Kunming, , China
The First Affiliated Hospital of Nanchang University, Nanchang, , China
The Second Affiliated Hospital of Nanchang University, Nanchang, , China
Jiangsu Province Hospital, Nanjing, , China
Fudan University Shanghai Cancer Center, Shanghai, , China
Shanghai Pulmonary Hospital, Shanghai, , China
Liaoning Cancer Hospital and Institute, Shenyang, , China
Shanxi Cancer hospital, Taiyuan, , China
Tianjin Medical University Cancer Institute & Hospital, Tianjin, , China
The 1st Affiliated hospital of Wenzhou Medical University, Wenzhou, , China
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China
Tangdu Hospital of The fourth Military Medical University Peoples Liberation Army of China, Xi'an, , China
Xiamen Humanity Hospital, Xiamen, , China
Henan Cancer Hospital, Zhengzhou, , China
Henan Provincial People's Hospital, Zhengzhou, , China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, , China