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Spots Global Cancer Trial Database for Study of Sitravatinib With or Without Other Anticancer Therapies Receiving Clinical Benefit From Parent Study

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Trial Identification

Brief Title: Study of Sitravatinib With or Without Other Anticancer Therapies Receiving Clinical Benefit From Parent Study

Official Title: A Multicenter, Open-label Rollover Study of Sitravatinib Alone or in Combination With Other Anticancer Therapies in Patients With Advanced or Metastatic Solid Malignancies

Study ID: NCT04887870

Study Description

Brief Summary: A Study of Sitravatinib Alone or in Combination with Other Anticancer Therapies in Advanced or Metastatic Malignancies

Detailed Description: Sitravatinib is a spectrum-selective receptor tyrosine kinase (RTK) inhibitor that inhibits several closely related RTKs including the TAM family (Tyro3/Axl/MERTK), VEGFR2, KIT, and MET. The current study is designed to allow continued access to sitravatinib and to evaluate the safety and tolerability of sitravatinib alone or in combination with other anticancer therapies in patients who are deriving clinical benefit in a previous parent clinical trial.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Beverly Hills Cancer Center, Beverly Hills, California, United States

Rocky Mountain Cancer Centers, Aurora, Colorado, United States

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Karmanos Cancer Institute, Detroit, Michigan, United States

University of Minnesota Health Clinics and Surgery Center, Minneapolis, Minnesota, United States

GU Research Network/Urology Cancer Center, Omaha, Nebraska, United States

New York Oncology Hematology, P.C., Clifton Park, New York, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

The Ohio State University Wexner Medical Center - Thoracic Oncology Clinic, Columbus, Ohio, United States

Texas Oncology - Denison Cancer Center, Denison, Texas, United States

UT MD Anderson Cancer Center, Houston, Texas, United States

NEXT Oncology, San Antonio, Texas, United States

NEXT Virginia, Fairfax, Virginia, United States

Contact Details

Name: Ronald Shazer, MD

Affiliation: Mirati Therapeutics Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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