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Brief Title: Study of an Anti-HER3 Antibody, HMBD-001, With Docetaxel +/- Cetuximab in Advanced Squamous Non-small Cell Lung Cancers
Official Title: A Phase 1b Study to Evaluate HMBD-001 in Combination With Docetaxel With or Without Cetuximab in Participants With Advanced Squamous Non-small Cell Lung Cancers
Study ID: NCT05910827
Brief Summary: This is a phase 1b multi-center, open-label study of HMBD-001 in combination with docetaxel with or without cetuximab in participants with locally advanced or metastatic squamous Non-Small Cell Lung Cancers
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
GenesisCare North Shore, Sydney, New South Wales, Australia
ICON Cancer Centre South Brisbane, Brisbane, Queensland, Australia
Southern Oncology Clinical Research Unit, Adelaide, South Australia, Australia
Peninsula & South Eastern Haematology and Oncology Group, Frankston, Victoria, Australia
Cabrini Health, Malvern, Victoria, Australia
Linear Clinical Research, Perth, Western Australia, Australia
National Cancer Centre Singapore, Singapore, , Singapore
Tan Tock Seng Hospital, Singapore, , Singapore