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Brief Title: A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate Cancer
Official Title: A Phase 1, Open-Label, Multicenter, Dose-Escalation and Expansion Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 in Patients With Advanced or Metastatic Prostate Cancer
Study ID: NCT05800665
Brief Summary: The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and preliminary activity of RO7656594 in participants with advanced or metastatic prostate cancer. It will also identify recommended doses and regimens for RO7656594 for subsequent studies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
HonorHealth, Scottsdale, Arizona, United States
Yale Cancer Center, New Haven, Connecticut, United States
Florida Cancer Specialists & Research Institute - Lake Nona Cancer Center, Orlando, Florida, United States
Sarah Cannon Research Institute / Tennessee Oncology, Nashville, Tennessee, United States
St Vincent's Hospital Sydney, Darlinghurst, New South Wales, Australia
Austin Hospital, Heidelberg, Victoria, Australia
Seoul National University Hospital, Seoul, , Korea, Republic of
Asan Medical Center - PPDS, Seoul, , Korea, Republic of
Name: Clinical Trials
Affiliation: Genentech, Inc.
Role: STUDY_DIRECTOR