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Spots Global Cancer Trial Database for Nivolumab Combined With Ipilimumab Versus Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (CheckMate 214)

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Trial Identification

Brief Title: Nivolumab Combined With Ipilimumab Versus Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (CheckMate 214)

Official Title: A Phase 3, Randomized, Open-Label Study of Nivolumab Combined With Ipilimumab Versus Sunitinib Monotherapy in Subjects With Previously Untreated, Advanced or Metastatic Renal Cell Carcinoma

Study ID: NCT02231749

Study Description

Brief Summary: The purpose of this study is to compare the objective response rate, progression free survival and the overall survival of Nivolumab combined with Ipilimumab to Sunitinib monotherapy in patients with previously untreated Renal Cell Cancer.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Local Institution - 0006, Duarte, California, United States

Local Institution - 0057, La Jolla, California, United States

Local Institution - 0044, Los Angeles, California, United States

Local Institution - 0035, Los Angeles, California, United States

Local Institution - 0067, Stanford, California, United States

Local Institution - 0138, New Haven, Connecticut, United States

Local Institution - 0034, Washington, District of Columbia, United States

Local Institution - 0049, Tampa, Florida, United States

Local Institution - 0068, Atlanta, Georgia, United States

Local Institution - 0038, Indianapolis, Indiana, United States

Local Institution - 0042, Iowa City, Iowa, United States

Local Institution - 0163, Fairway, Kansas, United States

Local Institution - 0048, Baltimore, Maryland, United States

Local Institution - 0004, Baltimore, Maryland, United States

Local Institution - 0135, Boston, Massachusetts, United States

Local Institution - 0110, Boston, Massachusetts, United States

Local Institution - 0161, Boston, Massachusetts, United States

Local Institution - 0173, Boston, Massachusetts, United States

Local Institution - 0046, Ann Arbor, Michigan, United States

Local Institution - 0043, Detroit, Michigan, United States

Local Institution - 0036, Buffalo, New York, United States

Local Institution - 0001, New York, New York, United States

Local Institution - 0008, Charlotte, North Carolina, United States

Local Institution - 0045, Durham, North Carolina, United States

Local Institution - 0007, Cleveland, Ohio, United States

Local Institution - 0164, Columbus, Ohio, United States

Local Institution - 0039, Portland, Oregon, United States

Local Institution - 0054, Allentown, Pennsylvania, United States

Local Institution - 0005, Philadelphia, Pennsylvania, United States

Local Institution - 0031, Pittsburgh, Pennsylvania, United States

Local Institution - 0055, Charleston, South Carolina, United States

Local Institution - 0159, Chattanooga, Tennessee, United States

Local Institution - 0066, Nashville, Tennessee, United States

Local Institution - 0056, Dallas, Texas, United States

Local Institution - 0032, Dallas, Texas, United States

Local Institution - 0003, Houston, Texas, United States

Local Institution - 0041, Seattle, Washington, United States

Local Institution - 0099, Berazategui, Buenos Aires, Argentina

Local Institution - 0098, Capital Federal, Buenos Aires, Argentina

Local Institution - 0139, Ciudad Autonoma De Buenos Aire, Buenos Aires, Argentina

Local Institution - 0095, San Miguel De Tucuman, Tucuman, Argentina

Local Institution - 0096, San Miguel de Tucuman, Tucuman, Argentina

Local Institution - 0097, Caba, , Argentina

Local Institution - 0100, Cordoba, , Argentina

Local Institution - 0073, Kogarah, New South Wales, Australia

Local Institution - 0070, Westmead, New South Wales, Australia

Local Institution - 0076, Herston, Queensland, Australia

Local Institution - 0075, Southport, Queensland, Australia

Local Institution - 0140, Elizabeth Vale, South Australia, Australia

Local Institution - 0072, Box Hill, Victoria, Australia

Local Institution - 0071, Clayton, Victoria, Australia

Local Institution - 0104, Nedlands, Western Australia, Australia

Local Institution - 0074, Murdoch, , Australia

Local Institution - 0108, Linz, , Austria

Local Institution - 0107, Wels, , Austria

Local Institution - 0109, Wien, , Austria

Local Institution - 0020, Gent, , Belgium

Local Institution - 0019, Leuven, , Belgium

Local Institution - 0152, Belo Horizonte, Minas Gerais, Brazil

Local Institution - 0150, Porto Alegre, RIO Grande DO SUL, Brazil

Local Institution - 0151, Porto Alegre, Rio Grande Do Sul, Brazil

Local Institution - 0153, Sao Paulo, São Paulo, Brazil

Local Institution - 0157, Rio de Janeiro, , Brazil

Local Institution - 0155, Sao Paulo, , Brazil

Local Institution - 0156, Sao Paulo, , Brazil

Local Institution - 0149, Calgary, Alberta, Canada

Local Institution - 0133, Edmonton, Alberta, Canada

Local Institution - 0182, Kelowna, British Columbia, Canada

Local Institution - 0128, Vancouver, British Columbia, Canada

Local Institution - 0131, Moncton, New Brunswick, Canada

Local Institution - 0172, Toronto, Ontario, Canada

Local Institution - 0148, Toronto, Ontario, Canada

Local Institution - 0132, Montreal, Quebec, Canada

Local Institution - 0101, Santiago, Metropolitana, Chile

Local Institution - 0102, Santiago, Metropolitana, Chile

Local Institution - 0144, Santiago, Metropolitana, Chile

Local Institution - 0103, Vina del Mar, , Chile

Local Institution - 0080, Bogota, , Colombia

Local Institution - 0162, Medellin, , Colombia

Local Institution - 0081, Medellin, , Colombia

Local Institution - 0050, Liberec, Liberecký Kraj, Czechia

Local Institution - 0053, Brno, , Czechia

Local Institution - 0051, Hradec Kralove, , Czechia

Local Institution - 0052, Olomouc, , Czechia

Local Institution - 0136, Aarhus N, , Denmark

Local Institution - 0158, Herlev, , Denmark

Local Institution - 0137, Odense, , Denmark

Local Institution - 0027, Helsinki, Uusimaa, Finland

Local Institution - 0028, Tampere, , Finland

Local Institution - 0170, Besançon, , France

Local Institution - 0062, Bordeaux, , France

Local Institution - 0169, La Roche-Sur-Yon Cedex 9, , France

Local Institution - 0060, Marseille Cedex 9, , France

Local Institution - 0063, Saint Herblain, , France

Local Institution - 0065, Strasbourg, , France

Local Institution - 0059, Toulouse Cedex 9, , France

Local Institution - 0058, Villejuif, , France

Local Institution - 0061, Paris, Île-de-France, France

Local Institution - 0125, Aachen, , Germany

Local Institution - 0126, Erlangen, , Germany

Local Institution - 0141, Frankfurt, , Germany

Local Institution - 0147, Hamburg, , Germany

Local Institution - 0142, Hannover, , Germany

Local Institution - 0123, Heidelberg, , Germany

Local Institution - 0127, Homburg, , Germany

Local Institution - 0129, Jena, , Germany

Local Institution - 0143, Magdeburg, , Germany

Local Institution - 0124, Muenchen, , Germany

Local Institution - 0146, Muenster, , Germany

Local Institution - 0130, Ulm, , Germany

Local Institution - 0184, Gyula, Békés, Hungary

Local Institution - 0083, Budapest, , Hungary

Local Institution - 0082, Debrecen, , Hungary

Local Institution - 0084, Pecs, , Hungary

Local Institution - 0015, Wilton, Cork, Ireland

Local Institution - 0017, Dublin 7, Dublin, Ireland

Local Institution - 0018, Dublin 7, Dublin, Ireland

Local Institution - 0016, Dublin, , Ireland

Local Institution - 0120, Haifa, , Israel

Local Institution - 0117, Kfar Saba, , Israel

Local Institution - 0121, Petach Tikva, , Israel

Local Institution - 0118, Ramat-gan, , Israel

Local Institution - 0119, Zerifin, , Israel

Local Institution - 0022, Arezzo, , Italy

Local Institution - 0024, Meldola (fc), , Italy

Local Institution - 0023, Milano, , Italy

Local Institution - 0064, Napoli, , Italy

Local Institution - 0079, Padova, , Italy

Local Institution - 0025, Pavia, , Italy

Local Institution - 0026, Roma, , Italy

Local Institution - 0192, Akita-shi, Akita, Japan

Local Institution - 0209, Hirosaki-shi, Aomori, Japan

Local Institution - 0187, Chiba-shi, Chiba, Japan

Local Institution - 0196, Fukuoka-shi, Fukuoka, Japan

Local Institution - 0188, Sapporo-shi, Hokai-do, Japan

Local Institution - 0183, Sapporo-shi, Hokkaido, Japan

Local Institution - 0206, Kobe, Hyogo, Japan

Local Institution - 0205, Tsukuba-shi, Ibaraki, Japan

Local Institution - 0200, Morioka-shi, Iwate, Japan

Local Institution - 0186, Yokohama-shi, Kanagawa, Japan

Local Institution - 0189, Kumamoto-shi, Kumamoto, Japan

Local Institution - 0191, Kyoto-shi, Kyoto, Japan

Local Institution - 0199, Niigata-shi, Niigata, Japan

Local Institution - 0204, Okayama-shi, Okayama, Japan

Local Institution - 0190, Osaka-sayama, Osaka, Japan

Local Institution - 0201, Suita-shi, Osaka, Japan

Local Institution - 0208, Hamamatsu-shi, Shizuoka, Japan

Local Institution - 0194, Tokushima-shi, Tokushima, Japan

Local Institution - 0202, Bunkyo-ku, Tokyo, Japan

Local Institution - 0197, Bunkyo-ku, Tokyo, Japan

Local Institution - 0195, Bunkyo-ku, Tokyo, Japan

Local Institution - 0207, Koto-ku, Tokyo, Japan

Local Institution - 0185, Shinjuku-Ku, Tokyo, Japan

Local Institution - 0193, Shinjuku-ku, Tokyo, Japan

Local Institution - 0198, Tokyo, , Japan

Local Institution - 0203, Yamagata, , Japan

Local Institution - 0178, Seoul, , Korea, Republic of

Local Institution - 0177, Seoul, , Korea, Republic of

Local Institution - 0176, Seoul, , Korea, Republic of

Local Institution - 0168, Mexico D.f., Distrito Federal, Mexico

Local Institution - 0171, Monterrey, Nuevo Leon, Mexico

Local Institution - 0175, Queretaro, Querétaro, Mexico

Local Institution - 0167, Oaxaca, , Mexico

Local Institution - 0029, Amsterdam, , Netherlands

Local Institution - 0040, Groningen, , Netherlands

Local Institution - 0030, Nijmegen, , Netherlands

Local Institution - 0093, Krakow, , Poland

Local Institution - 0112, Poznan, , Poland

Local Institution - 0106, Wroclaw, , Poland

Local Institution - 0089, Barcelona, , Spain

Local Institution - 0088, Barcelona, , Spain

Local Institution - 0086, Madrid, , Spain

Local Institution - 0085, Madrid, , Spain

Local Institution - 0087, Madrid, , Spain

Local Institution - 0111, Oviedo, , Spain

Local Institution - 0090, Sevilla, , Spain

Local Institution - 0134, Solna, , Sweden

Local Institution - 0179, Taipei, , Taiwan

Local Institution - 0180, Taipei, , Taiwan

Local Institution - 0181, Taoyuan, , Taiwan

Local Institution - 0115, Ankara, , Turkey

Local Institution - 0114, Antalya, , Turkey

Local Institution - 0122, Istanbul, , Turkey

Local Institution - 0010, London, Greater London, United Kingdom

Local Institution - 0009, Glasgow, Lanarkshire, United Kingdom

Local Institution - 0077, London, , United Kingdom

Local Institution - 0021, Manchester, , United Kingdom

Local Institution - 0011, Northwood, , United Kingdom

Local Institution - 0012, Swansea, , United Kingdom

Contact Details

Name: Bristol-Myers Squibb

Affiliation: Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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