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Brief Title: Evaluate Safety, Tolerability, PK, Preliminary Clinical Activity of OB318 in Patients With Advanced Solid Malignancies
Official Title: A Phase I, Open-Label, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Clinical Activity of OB318 in Patients With Advanced Solid Malignancies
Study ID: NCT02347228
Brief Summary: The objectives of this Phase I study are to determine the maximum tolerable dose (MTD) and to evaluate pharmacokinetics (PK), safety/ tolerability and preliminary efficacy of OB318 in patients with advanced solid malignancies.
Detailed Description:
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Tri-Service General Hospital, Taipei, , Taiwan
Taipei Medical University-Shuang Ho Hospital, Taipei, , Taiwan
Name: Ching-Liang Ho
Affiliation: Tri-Service General Hospital
Role: PRINCIPAL_INVESTIGATOR