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Brief Title: Phase I Study With AZD2171 in Patients With Advanced Solid Malignant Tumors and Liver Metastases
Official Title: A Phase I Single Centre 2-part Open Study to Assess the Safety and Tolerability of AZD2171 Following Single and Multiple Oral Doses in Patients With Advanced Solid Malignant Tumors and Liver Metastases
Study ID: NCT00501605
Brief Summary: Single centre recruiting approximately 80 patients who are given a rising single, followed by multiple, ascending oral dose of AZD2171, assessing the safety and tolerability of AZD2171 in patients with solid tumors and metastatic liver disease.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research Site, Freiburg, , Germany
Name: Nick Botwood, BSc, MBBS, MRCP, MFPM
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR
Name: J. Drevs, PD
Affiliation: Klinik fur.Internistische Onkologie
Role: PRINCIPAL_INVESTIGATOR