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Brief Title: Study of CLR457 Administered Orally in Adult Patients With Advanced Solid Malignancies
Official Title: A Phase I/II Multicenter, Open-label Study of CLR457, Administered Orally in Adult Patients With Advanced Solid Malignancies
Study ID: NCT02189174
Brief Summary: To estimate the maximum tolerated dose (MTD) or recommended dose for phase II (RP2D) of CLR457 and to investigate the anti-tumor activity of CLR457
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Massachusetts General Hospital SC-9, Boston, Massachusetts, United States
Memorial Sloan Kettering SC-4, New York, New York, United States
Tennessee Oncology SC, Nashville, Tennessee, United States
Novartis Investigative Site, Toronto, Ontario, Canada
Novartis Investigative Site, Kashiwa, Chiba, Japan
Novartis Investigative Site, Singapore, , Singapore
Novartis Investigative Site, Barcelona, Catalunya, Spain
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR