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Brief Title: A Phase II Study of Envofolimab and BD0801 With/Without Chemotherapy in Patients With Advanced Solid Tumors
Official Title: An Open Label, Multi-cohort, Multicenter Phase II Study to Evaluate the Efficacy and Safety of Envofolimab in Combination With BD0801 Injection With/Without Chemotherapy in Patients With Advanced Solid Tumors
Study ID: NCT05148195
Brief Summary: This is an open label, multi-cohort, multicenter Phase II study, the purpose of this study is to assess the efficacy and safety of envofolimab in combination with BD0801 injection with/without chemotherapy for the treatment of advanced solid tumors
Detailed Description: The efficacy of immune checkpoint inhibitors combined with antivascular agents has been preliminarily demonstrated in a variety of solid tumors. Based on the huge clinical needs, the efficacy of envofolimab combined with BD0801 in patients with advanced hepatocellular carcinoma, non-small cell lung cancer and advanced colorectal cancer deserves further exploration.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Beijing Cancer Hospital, Beijing, , China
The First Affiliated Hospital of Bengbu Medical College, Bengbu, , China
Jilin Cancer Hospital, Changchun, , China
Hunan Cancer Hospital, Changsha, , China
Sichuan Cancer Hospital, Chengdu, , China
Dezhou People'S Hospital, Dezhou, , China
First Affiliated Hospital of Gannan Medical Universit, Ganzhou, , China
Nanfang Hospital of Southern Medical University, Guangzhou, , China
Sun Yat-sen University affiliated with the Sixth Hospital, Guangzhou, , China
Sun Yat-sen University Cancer Center, Guangzhou, , China
Shaw Hospital Affiliated to Medical College of Zhejiang Universit, Hangzhou, , China
Zhejiang Provincial People'S Hospital, Hangzhou, , China
Harbin Medical University Cancer Hospital, Harbin, , China
Anhui Chest Hospital, Hefei, , China
Anhui Provincial Cancer Hospital, Hefei, , China
The First Affliated Hospital Of Anhui Medical University, Hefei, , China
Shandong Cancer Hospital, Jinan, , China
Mianyang Central Hospital, Mianyang, , China
Liaoning Cancer Hospital, Shenyang, , China
The Fourth Hospital of Hebei Medical University, Shijia Zhuang, , China
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, , China
Yantai Yuhuagnding Hospital, Yantai, , China
Henan Cancer Hospital, Zhengzhou, , China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, , China
Name: Zhengguang Lv
Affiliation: Jiangsu Simcere Pharmaceutical Co., Ltd.
Role: STUDY_DIRECTOR