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Brief Title: Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TJ107 in Chinese Patients With Advanced Solid Tumors
Official Title: A Phase I/IIa, Open-label, Dose-Escalation and Dose Expansion Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TJ107 in Chinese Patients With Advanced Solid Tumors
Study ID: NCT04001075
Brief Summary: This is a two-part study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of TJ107 in Chinese patients with advanced solid tumors. Approximately a total of 36 \~ 60 patients will be enrolled into the dose escalation cohorts (Part A), and expansion cohorts (Part B).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The sixth Affiliated Hospital, Sun Yat-sen University, Guanzhou, Guangdong, China
the First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China
Shanghai East Hospital, Shanghai, Shanghai, China
Sir Run Run Shaw Hospital, affiliated with the Zhejiang University School of the Medical, Hangzhou, Zhejiang, China