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Spots Global Cancer Trial Database for A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 in Participants With Selected Advanced Solid Tumors

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Trial Identification

Brief Title: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 in Participants With Selected Advanced Solid Tumors

Official Title: A Phase 1, Open-Label, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 as Monotherapy in Patients With Selected Advanced Solid Tumors

Study ID: NCT04972981

Interventions

ADCT-901

Study Description

Brief Summary: The primary objectives of this study are to identify the recommended phase 2 dose (RP2D) and/or maximum tolerated dose (MTD), and to characterize the safety and the tolerability of ADCT-901.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Sarah Cannon at HealthONE, Denver, Colorado, United States

Yale Cancer Center, New Haven, Connecticut, United States

Emory University, Winship Cancer Institute, Atlanta, Georgia, United States

Northwestern University, Chicago, Illinois, United States

University Hospitals of Cleveland Medical Center (UHCMC), Cleveland, Ohio, United States

Sarah Cannon at University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

NEXT Oncology, San Antonio, Texas, United States

Institut Catala D'oncologia (ICO) - Hospital Duran I Reynals Location, Badalona, Barcelona, Spain

Hospital Universitari Vall D'hebron - Vall D'hebron Institut D'oncologia (VHIO), Barcelona, , Spain

(START) Madrid - Hospital Universitario Fundación Jiménez Díaz Location, Madrid, , Spain

Universidad Complutense de Madrid - Hospital Universitario 12 de Octubre, Madrid, , Spain

Imperial College Healthcare NHS Trust - St Mary's Hospital, London, England, United Kingdom

Sarah Cannon Research Institute (SCRI) - London (SCRI-UK), London, England, United Kingdom

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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