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Brief Title: Combination Trial of Patupilone and Carboplatin in Adult Patients With Advanced Solid Tumors
Official Title: A Phase Ib, Multicenter, Open-label, Dose-finding Study of Patupilone Administered Intravenously Every 3 Weeks in Combination With Carboplatin AUC 6 in Adult Patients With Advanced Solid Tumors
Study ID: NCT00426582
Brief Summary: This study will evaluate the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of patupilone combined with carboplatin in adult patients with advanced solid tumors who progressed despite standard therapy or for whom no standard therapy exists or who might benefit from treatment with carboplatin
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Norwalk Hospital, Norwalk, Connecticut, United States
Associates in Oncology, Rockville, Maryland, United States
Wertz Clinical Cancer Center (Wayne State University), Detroit, Michigan, United States
Siteman Cancer Center (Washington University School of Medicine), Saint Louis, Missouri, United States
Cancer Research and Treatment Center (University of New Mexico), Albuquerque, New Mexico, United States
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmeceuticals
Role: STUDY_DIRECTOR