Spots Global Cancer Trial Database for A Study of ABT-165 in Subjects With Solid Tumors
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Trial Identification
Brief Title: A Study of ABT-165 in Subjects With Solid Tumors
Official Title: A Multicenter, Phase 1/1b, Open-Label, Dose-Escalation Study of ABT-165, a Dual Variable Domain Immunoglobulin in Subjects With Advanced Solid Tumors
Study ID: NCT01946074
Conditions
Study Description
Brief Summary: This is a Phase 1/1b open-label study evaluating the safety, pharmacokinetics (PK), and preliminary efficacy of ABT-165 when administered as monotherapy and in combination with paclitaxel or 5-fluoruracil, folinic acid and irinotecan (FOLFIRI) or ABBV-181 with/without paclitaxel in subjects with advanced solid tumors. Enrollment to Cohorts A, B were completed and for Cohorts C and D are recruiting.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
HonorHealth Research Institute - Pima /ID# 105677, Scottsdale, Arizona, United States
Scottsdale Healthcare /ID# 105678, Scottsdale, Arizona, United States
University of California, Los Angeles /ID# 141389, Los Angeles, California, United States
University of California, Davis Comprehensive Cancer Center /ID# 141164, Sacramento, California, United States
Stanford University School of Med /ID# 123758, Stanford, California, United States
Illinois Cancer Care, PC /ID# 151970, Peoria, Illinois, United States
Horizon Oncology Research Center /ID# 138022, Lafayette, Indiana, United States
Duke Cancer Center /ID# 105679, Durham, North Carolina, United States
Tennessee Oncology-Nashville Centennial /ID# 143280, Nashville, Tennessee, United States
Mary Crowley Cancer Research /ID# 123757, Dallas, Texas, United States
Contact Details
Name: ABBVIE INC.
Affiliation: AbbVie
Role: STUDY_DIRECTOR
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