Spots Global Cancer Trial Database for A Phase 1 Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Solid Tumors
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Trial Identification
Brief Title: A Phase 1 Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Solid Tumors
Official Title: A Phase I Study of MEDI4736 (Anti-PD-L1 Antibody) in Combination With Tremelimumab (Anti-CTLA-4 Antibody) in Subjects With Advanced Solid Tumors
Study ID: NCT02261220
Conditions
Study Description
Brief Summary: This is a multicenter, open-label, dose-exploration and dose-expansion study to evaluate the safety, tolerability, antitumor activity, PK and immunogenicity of MEDI4736 in combination with tremelimumab in subjects with select advanced solid tumors.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Scottsdale, Arizona, United States
Research Site, Duarte, California, United States
Research Site, La Jolla, California, United States
Research Site, Los Angeles, California, United States
Research Site, Los Angeles, California, United States
Research Site, Whittier, California, United States
Research Site, Aurora, Colorado, United States
Research Site, New Haven, Connecticut, United States
Research Site, Miami Beach, Florida, United States
Research Site, Tampa, Florida, United States
Research Site, Chicago, Illinois, United States
Research Site, Chicago, Illinois, United States
Research Site, Iowa City, Iowa, United States
Research Site, Louisville, Kentucky, United States
Research Site, Ann Arbor, Michigan, United States
Research Site, Bronx, New York, United States
Research Site, New York, New York, United States
Research Site, New York, New York, United States
Research Site, Cincinnati, Ohio, United States
Research Site, Cleveland, Ohio, United States
Research Site, Portland, Oregon, United States
Research Site, Portland, Oregon, United States
Research Site, Philadelphia, Pennsylvania, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, Greenville, South Carolina, United States
Research Site, Dallas, Texas, United States
Research Site, Houston, Texas, United States
Research Site, San Antonio, Texas, United States
Research Site, Fairfax, Virginia, United States
Research Site, Seattle, Washington, United States
Research Site, London, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Quebec, , Canada
Research Site, Angers Cedex 02, , France
Research Site, BESANCON Cedex, , France
Research Site, Bordeaux Cedex, , France
Research Site, Lyon, , France
Research Site, Marseille, , France
Research Site, Montpellier, , France
Research Site, Pierre Benite, , France
Research Site, Vandoeuvre les Nancy, , France
Research Site, Villejuif, , France
Research Site, Jena, , Germany
Research Site, Münster, , Germany
Research Site, Tübingen, , Germany
Research Site, Haifa, , Israel
Research Site, Jerusalem, , Israel
Research Site, Kfar Saba, , Israel
Research Site, Tel-Aviv, , Israel
Research Site, Busan, , Korea, Republic of
Research Site, Daegu, , Korea, Republic of
Research Site, Daegu, , Korea, Republic of
Research Site, Gwangju, , Korea, Republic of
Research Site, Seongnam-si, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Amsterdam, , Netherlands
Research Site, Amsterdam, , Netherlands
Research Site, Tilburg, , Netherlands
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Pamplona, , Spain
Research Site, Valencia, , Spain
Research Site, Glasgow, , United Kingdom
Research Site, London, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Middlesborough, , United Kingdom
Research Site, Oxford, , United Kingdom
Research Site, Wirral, , United Kingdom
Contact Details
Name: MedImmune LLC
Affiliation: MedImmune LLC
Role: STUDY_DIRECTOR
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