Spots Global Cancer Trial Database for A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors
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Trial Identification
Brief Title: A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors
Official Title: A PHASE 1 STUDY TO EVALUATE THE SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF ESCALATING DOSES OF PF-06939999 (PRMT5 INHIBITOR) IN PARTICIPANTS WITH ADVANCED OR METASTATIC NON-SMALL CELL LUNG CANCER, HEAD AND NECK SQUAMOUS CELL CARCINOMA, ESOPHAGEAL CANCER, ENDOMETRIAL CANCER, CERVICAL CANCER AND BLADDER CANCER
Study ID: NCT03854227
Study Description
Brief Summary: This is a Phase 1, open label, multi center, dose escalation and expansion, safety, tolerability, PK, and pharmacodynamics study of PF 06939999 in previously treated patients with advanced or metastatic cancer.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Scottsdale Healthcare Hospitals d/b/a HonorHealth, Scottsdale, Arizona, United States
Virginia G. Piper Cancer Pharmacy, Scottsdale, Arizona, United States
Keck Hospital of USC, Los Angeles, California, United States
LAC + USC Medical Center, Los Angeles, California, United States
USC Norris Comprehensive Cancer Center, Los Angeles, California, United States
USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States
Keck Medical Center of USC Pasadena, Pasadena, California, United States
AdventHealth Celebration Infusion Center, Celebration, Florida, United States
AdventHealth Medical Group Oncology Research at Celebration, Celebration, Florida, United States
University Of Miami Hospital and Clinics/Sylvester Comprehensive Cancer Center, Miami, Florida, United States
AdventHealth Hematology and Oncology, Orlando, Florida, United States
AdventHealth Orlando - Investigational Drug Services, Orlando, Florida, United States
AdventHealth Orlando Infusion Center, Orlando, Florida, United States
St. Joseph Mercy Hospital, Ann Arbor, Michigan, United States
St. Joseph Mercy Brighton, Brighton, Michigan, United States
Henry-Joyce Cancer Clinic, Nashville, Tennessee, United States
Oncology IDS Pharmacy, Nashville, Tennessee, United States
The University of Texas, Houston, Texas, United States
NEXT Oncology, San Antonio, Texas, United States
Inova Schar Cancer Institute, Fairfax, Virginia, United States
Seattle Cancer Care Alliance, Seattle, Washington, United States
University of Washington Medical Center, Seattle, Washington, United States
Contact Details
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR
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