Spots Global Cancer Trial Database for A Study of Mipasetamab Uzoptirine (ADCT-601) in Participants With Solid Tumors
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Trial Identification
Brief Title: A Study of Mipasetamab Uzoptirine (ADCT-601) in Participants With Solid Tumors
Official Title: A Phase 1b, Open-Label, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of Mipasetamab Uzoptirine (ADCT-601) Monotherapy and in Combination With Other Anti-Cancer Therapies in Patients With Selected Advanced Solid Tumors
Study ID: NCT05389462
Conditions
Study Description
Brief Summary: The primary objective of this study is to identify the recommended phase 2 dose (RP2D) and/or the maximum tolerated dose (MTD), and characterize the safety and tolerability of ADCT-601 monotherapy and in combination with gemcitabine.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Sarcoma Oncology Research Center, Santa Monica, California, United States
Stanford Cancer Center, Stanford Medicine at Stanford University, Stanford, California, United States
University of IOWA, Iowa City, Iowa, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Sarah Cannon at University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Vanderbilt University Medical Center (VUMC) - Ingram Cancer Center, Nashville, Tennessee, United States
Institut Bergonié, Bordeaux, Gironde, France
Institut Léon Bérard, Lyon, , France
Centre Antoine Lacassagne, Nice, , France
Hospital Universitario Vall d'Hebron, Barcelona, , Spain
Hospital Universitario Fundacion Jimenez Diaz, Madrid, , Spain
Hospital Universitario Madrid Sanchinarro, Madrid, , Spain
The Christie NHS Foundation Trust, Manchester, , United Kingdom
Contact Details
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