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Brief Title: A Study of BMS-986449 With and Without Nivolumab in Participants With Advanced Solid Tumors
Official Title: A Phase 1/2 Study of BMS-986449 Alone and in Combination With Nivolumab in Participants With Advanced Solid Tumors
Study ID: NCT05888831
Brief Summary: The purpose of this study is to evaluate the safety and efficacy of BMS-986449 alone and in combination with nivolumab in participants with advanced solid tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The Angeles Clinic and Research Institute - West Los Angeles Office, Los Angeles, California, United States
Yale New Haven Hospital-Smilow Cancer Center, New Haven, Connecticut, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey, United States
R.J. Zuckerberg Cancer Center, Lake Success, New York, United States
Cliniques universitaires Saint-Luc, Brussels, Bruxelles-Capitale, Région De, Belgium
UZ Gent, Gent, Oost-Vlaanderen, Belgium
Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest, Bordeaux, Aquitaine, France
Gustave Roussy, Villejuif, Paris, France
Institut Paoli-Calmettes, Marseille, Provence-Alpes-Côte-d'Azur, France
Centre Leon Berard, Lyon CEDEX 08, Rhône-Alpes, France
Humanitas, Rozzano, Milano, Italy
Azienda Ospedaliero Universitaria Senese, Siena, Toscana, Italy
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, , Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore, Roma, , Italy
Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL), Amsterdam, , Netherlands
University Medical Center Groningen, Groningen, , Netherlands
Hospital Universitario Virgen de la Victoria, Málaga, Andalucía, Spain
Institut Català d'Oncologia (ICO) - Badalona, Badalona, Barcelona [Barcelona], Spain
Clinica Universidad de Navarra, Pamplona, Navarra, Spain
Hospital Universitario Fundación Jiménez Díaz, Madrid, , Spain
Hospital Universitario HM Sanchinarro, Madrid, , Spain
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR