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Spots Global Cancer Trial Database for AMG 404 in Patients With Advanced Solid Tumors

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Trial Identification

Brief Title: AMG 404 in Patients With Advanced Solid Tumors

Official Title: A Phase 1 Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 404, a Programmed Death-1 (PD-1) Antibody, in Patients With Advanced Solid Tumors

Study ID: NCT03853109

Interventions

AMG 404

Study Description

Brief Summary: To evaluate the safety and tolerability of AMG 404, a monoclonal antibody that binds to PD-1 and inhibits its engagement with ligands, in patients with advanced solid tumors.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Sarcoma Oncology Research Center LLC, Santa Monica, California, United States

Sarah Cannon Research Institute at HealthONE, Denver, Colorado, United States

University of Louisville James Graham Brown Cancer Center, Louisville, Kentucky, United States

Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Chris OBrien Lifehouse, Camperdown, New South Wales, Australia

The Queen Elizabeth Hospital, Woodville South, South Australia, Australia

Universitair Ziekenhuis Antwerpen, Edegem, , Belgium

Nucleo de Oncologia da Bahia, Salvador, Bahia, Brazil

Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul, Porto Alegre, Rio Grande Do Sul, Brazil

Sociedade Beneficente de Senhoras Hospital Sirio Libanes, Sao Paulo, São Paulo, Brazil

Hospital de Base de Sao Jose do Rio Preto, São José do Rio Preto, São Paulo, Brazil

Instituto Coi, Rio de Janeiro, , Brazil

Tom Baker Cancer Centre, Calgary, Alberta, Canada

National Cancer Center Hospital East, Kashiwa-shi, Chiba, Japan

National Hospital Organization Shikoku Cancer Center, Matsuyama-shi, Ehime, Japan

Wakayama Medical University Hospital, Wakayama-shi, Wakayama, Japan

Seoul National University Hospital, Seoul, , Korea, Republic of

Severance Hospital Yonsei University Health System, Seoul, , Korea, Republic of

Asan Medical Center, Seoul, , Korea, Republic of

Samsung Medical Center, Seoul, , Korea, Republic of

The Catholic University of Korea Seoul St Marys Hospital, Seoul, , Korea, Republic of

Uniwersyteckie Centrum Kliniczne, Gdansk, , Poland

Narodowy Instytut Onkologii im Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy, Warszawa, , Poland

National University Hospital, Singapore, , Singapore

National Cancer Centre Singapore, Singapore, , Singapore

Hospital Universitari Vall d Hebron, Barcelona, Cataluña, Spain

Hospital Universitario La Paz, Madrid, , Spain

Taipei Veterans General Hospital, Taipei, , Taiwan

Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation, Taoyuan, , Taiwan

Doktor Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi, Ankara, , Turkey

Koc Universitesi Hastanesi, Istanbul, , Turkey

Ege Universitesi Ilac Gelistirme ve Farmakokinetik Arastirma Uygulama Merkezi (ARGEFAR), Izmir, , Turkey

Sarah Cannon Research Institute UK, London, , United Kingdom

Contact Details

Name: MD

Affiliation: Amgen

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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