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Brief Title: Study to Evaluate Efficacy and Tolerance of R-GemOx in DLBCL and MCL
Official Title: Prospective, Open-label, Multicentric, ph. II Study of R-GemOx and Dexametasone in Patients With Agressive Lymphomas Refractory or Relapsed to Previous Treatment and Non Eligible for High-dose Chemotherapy Followed by Autologous Stem Cell Transplanted
Study ID: NCT01562977
Brief Summary: The purpose of this study is to determine efficacy of rituximab, gemcitabine, oxaliplatin and dexametasone (R-GemOx) chemotherapy schedule.
Detailed Description: The purpose of this study is to determine efficacy (overall response rate (ORR) and complete response) tolerance and toxicity of rituximab, gemcitabine, oxaliplatin and dexametasone (R-GemOx) chemotherapy schedule.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain
Hospital Duran i Reynals, Sabadell, Barcelona, Spain
Hospital SAS de Jerez, Jerez de la Frontera, Cádiz, Spain
Hospital Dr. Jose Molina Orosa, Arrecife, Lanzarote, Spain
Fundación Hospital de Alcorcón, Alcorcón, Madrid, Spain
Hospital Puerta de Hierro de Majadahonda, Majadahonda, Madrid, Spain
Hospital Virgen de Arrixaca, El Palmar, Murcia, Spain
Complejo Hospitalario de A Coruña, A Coruña, , Spain
Hospital Santa Creu i Sant Pau, Barcelona, , Spain
Hospital Vall d´Hebrón, Barcelona, , Spain
Hospital 12 Octubre, Madrid, , Spain
Hospital Gregorio Marañón, Madrid, , Spain
Hospital La Paz, Madrid, , Spain
Hospital Ramón y Cajal, Madrid, , Spain
Hospital Morales Meseguer, Murcia, , Spain
Hospital Son Espasses, Palma de Mallorca, , Spain
Hospital Son Llàtzer, Palma de Mallorca, , Spain
Clinica Universitaria de Navarra, Pamplona, , Spain
Corporació Sanitari Parc Taulí, Sabadell, , Spain
Hospital Clínico de Salamanca, Salamanca, , Spain
Hospital Universitario de Canarias, Santa Cruz de Tenerife, , Spain
Hospital Marqués de Valdecilla, Santander, , Spain
Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, , Spain
Hospital Dr. Peset, Valencia, , Spain
Hospital La Fe, Valencia, , Spain
Hospital Virgen de la Concha, Zamora, , Spain
Hospital Clínico Lozano Blesa, Zaragoza, , Spain
Hospital Miguel Servet, Zaragoza, , Spain
Name: Andrés López Hernández, MD
Affiliation: Hospital Vall d´Hebrón
Role: PRINCIPAL_INVESTIGATOR
Name: Mª Dolores Caballero Barrigón, MD
Affiliation: Hospital Clínico de Salamanca
Role: PRINCIPAL_INVESTIGATOR
Name: Jorge Gayoso Cruz, MD
Affiliation: Hospital Universitario Gregorio Marañón
Role: PRINCIPAL_INVESTIGATOR
Name: Juan Alfonso Soler Campos, MD
Affiliation: Corporació Sanitari Parc Taulí
Role: PRINCIPAL_INVESTIGATOR
Name: Carlos Montalbán Sanz, MD
Affiliation: Hospital Universitario Ramon y Cajal
Role: PRINCIPAL_INVESTIGATOR
Name: Juan Manuel Sancho Cía, MD
Affiliation: Germans Trias i Pujol Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Isidro Jarque, MD
Affiliation: Hospital La Fe de Valencia
Role: PRINCIPAL_INVESTIGATOR
Name: Secundino Ferrer, MD
Affiliation: Hospital Dr. Peset
Role: PRINCIPAL_INVESTIGATOR
Name: Carlos Grande, MD
Affiliation: Hospital 12 de Octubre
Role: PRINCIPAL_INVESTIGATOR
Name: Pilar Martínez Barranco, MD
Affiliation: Fundación Hospital de Alcorcón
Role: PRINCIPAL_INVESTIGATOR
Name: Miguel Ángel Canales Albendea, MD
Affiliation: Hospital La Paz
Role: PRINCIPAL_INVESTIGATOR
Name: Jose Antonio García Marco, MD
Affiliation: Hospital Puerta de Hierro de Majadahonda
Role: PRINCIPAL_INVESTIGATOR
Name: Roberto Hernández Martín, MD
Affiliation: Hospital Virgen de la Concha
Role: PRINCIPAL_INVESTIGATOR
Name: José Manuel Calvo Villas, MD
Affiliation: Hospital Dr. Jose Molina Orosa
Role: PRINCIPAL_INVESTIGATOR
Name: Miguel Hernández, García
Affiliation: Hospital Universitario de Canarias
Role: PRINCIPAL_INVESTIGATOR
Name: Elena Pérez Ceballos, MD
Affiliation: Hospital Morales Meseguer
Role: PRINCIPAL_INVESTIGATOR
Name: José M. Moraleda Jiménez, MD
Affiliation: Hospital Virgen de la Arrixaca
Role: PRINCIPAL_INVESTIGATOR
Name: Eulogio Conde García, MD
Affiliation: Hospital Marqués de Valdecilla
Role: PRINCIPAL_INVESTIGATOR
Name: Carlos Panizo Santos, MD
Affiliation: Clínica Universitaria Navarra
Role: PRINCIPAL_INVESTIGATOR
Name: Mª Rosario Varela, MD
Affiliation: Complejo Hospitalario A Coruña
Role: PRINCIPAL_INVESTIGATOR
Name: Jose Luis Bello López, MD
Affiliation: Complejo Hospitalario Universitario de Santiago
Role: PRINCIPAL_INVESTIGATOR
Name: Maria José Ramírez Sánchez, MD
Affiliation: Hospital del SAS Jerez
Role: PRINCIPAL_INVESTIGATOR
Name: Luis Palomera, MD
Affiliation: Hospital Clínico Lozano Blesa
Role: PRINCIPAL_INVESTIGATOR
Name: Pilar Giraldo, MD
Affiliation: Hospital Miguel Servet
Role: PRINCIPAL_INVESTIGATOR
Name: Antonio Gutiérrez, MD
Affiliation: Hospital Son Espasses
Role: PRINCIPAL_INVESTIGATOR
Name: Joan Bargay Leonart, MD
Affiliation: Hospital Son Llàtzer
Role: PRINCIPAL_INVESTIGATOR
Name: Eva González Barca, MD
Affiliation: Hospital Duran i Reynals
Role: PRINCIPAL_INVESTIGATOR
Name: Javier Briones Meijide, MD
Affiliation: Hospital Santa Creu i Sant Pau
Role: PRINCIPAL_INVESTIGATOR