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Brief Title: Study of Pixantrone in CD20+ Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma
Official Title: A Multicentre, Phase II, Open Label, Single Arm Study of Pixantrone in Patients With CD20-positive Relapsed or Refractory Aggressive Non-Hodgkin Lymphoma Treated With Rituximab, Ifosfamide and Etoposide.
Study ID: NCT03458260
Brief Summary: This study will evaluate the efficacy of Pixantrone with rituximab, ifosfamide and etoposide as measured by the overall metabolic response rate after 2 cycles of treatment or at permanent treatment discontinuation.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
AZ Sint Jan, Brugge, , Belgium
Institut Jules Bordet - Centre des tumeurs de l'ULB, Brussels, , Belgium
Centre Hospitalier de Jolimont, Haine-Saint-Paul, , Belgium
CH d'Avignon, Avignon, , France
Centre Hospitalier de la C么te Basque, Bayonne, , France
CHU Jean Minjoz, Besan莽on, , France
H么pital Haut-L茅v猫que, Bordeaux, , France
Centre Hospitalier William Morey, Chalon-sur-Sa么ne, , France
Clinique Victor Hugo, Le Mans, , France
CHRU de Lille, Lille, , France
CHU Lyon Sud, Lyon, , France
CHU de la Conception, Marseille, , France
Centre Lacassagne, Nice, , France
Hopital La Piti茅 Salp茅triere, Paris, , France
H么pital St louis, Paris, , France
CHU de Poitiers, Poitiers, , France
Centre Hospitalier Annecy Genevois, Pringy, , France
CH de Cornouaille, Quimper, , France
H么pital Robert Debr茅, Reims, , France
CHU de Rouen, Rouen, , France
CHU de Strasbourg, Strasbourg, , France
CHU de Tours, Tours, , France
Name: Luc-Matthieu Fornecker
Affiliation: CHU de Strasbourg
Role: PRINCIPAL_INVESTIGATOR
Name: Eric Van den Neste
Affiliation: UCL St Luc Bruxelles
Role: PRINCIPAL_INVESTIGATOR
Name: Sandy Amorin
Affiliation: H么pital St Louis - Paris
Role: PRINCIPAL_INVESTIGATOR